TABLE 5.
Comparison of BioFire PN panel and phenotypic results for detection of carbapenemase and ESBL-producing organismsa
| Specimen | PN panel bacterial target detected | PN panel resistance marker detected | Culture result | Phenotypic susceptibility (method) |
|---|---|---|---|---|
| B-08-008 | A. baumannii, 106 | blaKPC | A. baumannii, “few” | Carbapenem resistant (MIC) |
| K. pneumoniae, 104 | ND | NA | ||
| B-03-008 | E. cloacae, 106 | blaKPC | E. cloacae, ≥105 | Carbapenem resistant (MIC), ESBL positive (Etest ESBL) |
| P. aeruginosa, ≥107 | P. aeruginosa, ≥105 | Phenotypic tests not performed | ||
| B-01-015 | E. cloacae, 104 | blaNDM | E. cloacae, 103 | Carbapenem susceptible (MIC), ESBL negative (BMD) |
| B-08-056 | P. aeruginosa, 106 | blaCTX-M | P. aeruginosa, “moderate” | Carbapenem resistant (MIC) |
| B-01-040 | K. pneumoniae, 106 | ND | K. pneumoniae, 104 | Carbapenem susceptible (MIC), ESBL positive (BMD) |
| B-05-012 | E. cloacae, 105 | ND | E. cloacae, ≥105 | Carbapenem not tested, ESBL positive (KB) |
| B-08-024 | P. aeruginosa, ≥107 | ND | P. aeruginosa, “few” | Carbapenem resistant (MIC) |
| B-08-027 | K. oxytoca, 104 | ND | K. oxytoca, “rare” | Carbapenem susceptible (MIC), ESBL positive (MIC) |
| B-08-029 | P. aeruginosa, ≥107 | ND | P. aeruginosa, “few” | Carbapenem resistant (MIC) |
| B-08-053 | P. aeruginosa, ≥107 | ND | P. aeruginosa, “moderate” | Carbapenem resistant (MIC) |
a
ND, not detected; KB, Kirby-Bauer disk diffusion test; BMD, broth microdilution test; Etest ESBL, Etest ESBL test strip.