Table 2.
Pearson's correlation coefficients between the antioxidant and anti-inflammatory activities and in vitro gene expression of Agrimonia pilosa Ledeb. extract.
| DPPH | ABTS | FRAP | SOD | NO | TNF-α | IL-6 | IL-1β | GpX | |
|---|---|---|---|---|---|---|---|---|---|
| DPPH | 1 | ||||||||
| ABTS | 0.507 | 1 | |||||||
| FRAP | 0.671∗∗ | 0.757∗∗ | 1 | ||||||
| SOD | 0.429 | 0.546∗ | 0.876∗∗∗ | 1 | |||||
| NO | 0.534∗ | 0.455 | 0.842∗∗∗ | 0.930∗∗∗ | 1 | ||||
| TNF-α | −0.495 | −0.342 | −0.444 | −0.245 | −0.406 | 1 | |||
| IL-6 | −0.501 | −0.373 | −0.420 | −0.189 | −0.343 | 0.959∗∗∗ | 1 | ||
| IL-1β | −0.473 | −0.290 | −0.395 | −0.142 | −0.333 | 0.886∗∗∗ | 0.827∗∗∗ | 1 | |
| GpX | 0.562∗ | 0.530∗ | 0.852∗∗∗ | 0.714∗∗ | 0.728∗∗ | −0.349 | −0.279 | −0.307 | 1 |
DPPH: α,α-diphenyl-β-picrylhydrazyl; ABTS: 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid); FRAP; SOD: superoxide dismutase-like activity; NO: nitrite scavenging ability; TNF-α: tumor necrosis factor-alpha; IL-6: interleukin-6; IL-1β: interleukin-1beta; GpX: glutathione peroxidase. ∗Correlation is significant at p < 0.05. ∗∗Correlation is significant at p < 0.01. ∗∗∗Correlation is significant at p < 0.001.