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. 2020 May 9;39(3):221–228. doi: 10.14366/usg.19052

Table 2.

Summary of nodule-in-nodule appearance

Appearance
Nodule-in-nodule appearance specifically favors hepatocellular carcinoma as opposed to malignancy in general
Nodule-in-nodule appearance is a subset of mosaic appearance
Interpreters may, at their discretion, apply nodule-in-nodule appearance to upgrade the category (up to LR-4) for such observations
If uncertain about the feature, do not characterize it as having nodule-in-nodule appearance