Skip to main content
. 2020 Jun 26;43(3):e20190134. doi: 10.1590/1678-4685-GMB-2019-0134

Table 4. Major cell cycle bioprocesses in clusters 2 and 4 associated with IEs.

GO ID p-value corr p- k* n# Description Genes in test set
278 6,09E-38 2,63E-36 60 380 mitotic cell cycle CLTC|BUB1B|PSMD8|CDC20|PSMD9|PSMD7|CDC23|PSMD2|PSMD3|CDC27|PSMD1|AKT1|ANAPC7|RPS6|DNM2|PSMA5|PSMA6|PSMA3|ADAM17|PSMA4|PSMA1|PSME3|PSME1|RPL24|PSME2|ANAPC4|ANAPC5|ANAPC1|ANAPC2|PSMD10|ANAPC13|PSMD12|PSMD11|CUL5|PSMD13|CUL2|ANAPC10|PSMB10|ANAPC11|PSMB6|PSMB7|PSMB4|CCNB1|FZR1|PSMB5|PSMB2|PSMB3|PSMB1|CLTCL1|PSMB8|PSMB9|MAD2L2|PSMC6|PSMC3|PSMC4|PSMC1|CDC16|PSMC2|MDM2|MAD2L1
22402 4,93E-32 1,84E-30 65 582 cell cycle process CLTC|BUB1B|PSMD8|CDC20|PSMD9|PSMD7|CDC23|PSMD2|PSMD3|CDC27|PSMD1|AKT1|ANAPC7|RPS6|DNM2|RAD51B|PSMA5|PSMA6|PSMA3|ADAM17|RAD51C|PSMA4|PSMA1|PSME3|PSME1|RPL24|PSME2|ANAPC4|ANAPC5|TP53|ANAPC1|ANAPC2|PSMD10|ANAPC13|PSMD12|PSMD11|CUL5|PSMD13|CUL2|ANAPC10|PSMB10|ANAPC11|PSMB6|PSMB7|PSMB4|CCNB1|FZR1|PSMB5|PSMB2|PSMB3|PSMB1|CLTCL1|BARD1|PSMB8|PSMB9|MAD2L2|PSMC6|RAD51|PSMC3|PSMC4|PSMC1|CDC16|PSMC2|MDM2|MAD2L1
7049 1,12E-25 3,45E-24 67 794 cell cycle CLTC|BUB1B|BRCA1|PSMD8|CDC20|PSMD9|PSMD7|CDC23|PSMD2|PSMD3|CDC27|PSMD1|AKT1|ANAPC7|RPS6|DNM2|RAD51B|PSMA5|GAK|PSMA6|PSMA3|ADAM17|RAD51C|PSMA4|PSMA1|PSME3|PSME1|RPL24|PSME2|ANAPC4|ANAPC5|TP53|ANAPC1|ANAPC2|PSMD10|ANAPC13|PSMD12|PSMD11|CUL5|PSMD13|CUL2|ANAPC10|PSMB10|ANAPC11|PSMB6|PSMB7|PSMB4|CCNB1|FZR1|PSMB5|PSMB2|PSMB3|PSMB1|CLTCL1|BARD1|PSMB8|PSMB9|MAD2L2|PSMC6|RAD51|PSMC3|PSMC4|PSMC1|CDC16|PSMC2|MDM2|MAD2L1
22403 3,84E-07 8,30E-06 30 435 cell cycle phase ANAPC13|CUL5|CLTC|CUL2|BUB1B|ANAPC10|ANAPC11|CDC20|CCNB1|FZR1|CDC23|CDC27|CLTCL1|AKT1|ANAPC7|RPS6|DNM2|RAD51B|MAD2L2|ADAM17|RAD51C|RAD51|CDC16|MDM2|RPL24|ANAPC4|ANAPC5|ANAPC1|MAD2L1|ANAPC2
87 5,19E-06 1,03E-04 21 239 M phase of mitotic cell cycle ANAPC13|ANAPC7|CLTC|RPS6|BUB1B|ANAPC10|ANAPC11|CDC20|MAD2L2|CCNB1|FZR1|CDC23|CDC27|CDC16|CLTCL1|RPL24|ANAPC4|ANAPC5|ANAPC1|MAD2L1|ANAPC2
7049 5,73E-35 4,37E-33 71 794 cell cycle CCNK|CDKN1A|CCNT2|CCNT1|MCM7|CCNH|CETN2|BUB1B|BRCA1|CKS1B|CDC20|CDC23|EXO1|CHEK1|CDC27|EP300|NBN|POLK|POLE|TIPIN|LIG1|ANAPC7|LIG4|LIG3|RAD51B|MSH6|CCNA2|CCNA1|RAD51C|DBF4|MSH2|CKS2|TIMELESS|MCM3|ANAPC4|ANAPC5|MCM6|TP53|ANAPC1|ANAPC2|MCM2|ANAPC13|BLM|ANAPC10|ANAPC11|CCNB2|CCNB1|CDC45|POLD1|CLSPN|BARD1|UBE2I|UBE2B|RPA1|MRE11A|CDC7|CDC6|MAD2L2|POLA1|RAD50|CDK6|RAD51|CDC16|CDK2|MDM2|CDK1|ATM|MNAT1|ATR|MAD2L1|TAF1
22403 2,64E-31 1,79E-29 53 435 cell cycle phase CCNK|CDKN1A|CETN2|BUB1B|CDC20|CDC23|EXO1|CHEK1|CDC27|NBN|POLK|POLE|TIPIN|ANAPC7|LIG3|RAD51B|MSH6|CCNA2|CCNA1|RAD51C|DBF4|CKS2|TIMELESS|ANAPC4|ANAPC5|ANAPC1|ANAPC2|ANAPC13|BLM|ANAPC10|ANAPC11|CCNB2|CCNB1|POLD1|UBE2I|UBE2B|RPA1|MRE11A|CDC7|CDC6|MAD2L2|POLA1|RAD50|CDK6|RAD51|CDC16|CDK2|MDM2|CDK1|ATM|MNAT1|MAD2L1|TAF1
22402 7,25E-28 4,15E-26 56 582 cell cycle process CCNK|CDKN1A|CETN2|BUB1B|CDC20|CDC23|EXO1|CHEK1|CDC27|NBN|POLK|POLE|TIPIN|ANAPC7|LIG3|RAD51B|MSH6|CCNA2|CCNA1|RAD51C|DBF4|MSH2|CKS2|TIMELESS|ANAPC4|ANAPC5|TP53|ANAPC1|ANAPC2|ANAPC13|BLM|ANAPC10|ANAPC11|CCNB2|CCNB1|POLD1|BARD1|UBE2I|UBE2B|RPA1|MRE11A|CDC7|CDC6|MAD2L2|POLA1|RAD50|CDK6|RAD51|CDC16|CDK2|MDM2|CDK1|ATM|MNAT1|MAD2L1|TAF1
51726 1,75E-27 9,46E-26 50 446 regulation of cell cycle CCNK|CDKN1A|CCNT2|CCNT1|BUB1B|BRCA1|CKS1B|CCND3|CDC23|CASP3|CHEK1|NBN|TIPIN|DDB1|CCNA2|MSH2|CKS2|TIMELESS|TP53|ANAPC2|BLM|ANAPC10|BRIP1|CCNB1|CDC45|RBBP8|CLSPN|BARD1|JUN|CREBBP|UBE2B|MRE11A|CDC7|GTF2H1|CDC6|MAD2L2|CDK7|COPS5|CDK6|ERCC3|CDC16|FAM175A|CDK2|ERCC2|MDM2|CDK1|ATM|MNAT1|ATR|MAD2L1
75 5,24E-20 2,13E-18 25 107 cell cycle checkpoint CDKN1A|BLM|BUB1B|BRCA1|BRIP1|CCNB1|CDC45|CHEK1|RBBP8|NBN|CLSPN|TIPIN|CDC6|DDB1|MAD2L2|CCNA2|MSH2|ERCC3|FAM175A|ERCC2|CDK1|ATM|TP53|ATR|MAD2L1
278 4,71E-19 1,88E-17 39 380 mitotic cell cycle ANAPC13|CCNK|CDKN1A|BLM|CETN2|BUB1B|ANAPC10|ANAPC11|CDC20|CCNB2|CCNB1|CDC23|POLD1|CDC27|POLK|POLE|TIPIN|UBE2I|ANAPC7|CDC7|CDC6|MAD2L2|CCNA2|POLA1|CCNA1|CDK6|DBF4|CDC16|CDK2|TIMELESS|MDM2|CDK1|ANAPC4|ANAPC5|MNAT1|ANAPC1|MAD2L1|ANAPC2|TAF1
87 3,12E-14 1,00E-12 28 239 M phase of mitotic cell cycle ANAPC13|CCNK|CETN2|BUB1B|ANAPC10|ANAPC11|CDC20|CCNB2|CCNB1|CDC23|CDC27|POLK|TIPIN|UBE2I|ANAPC7|CDC6|MAD2L2|CCNA2|CCNA1|CDC16|CDK2|TIMELESS|CDK1|ANAPC4|ANAPC5|ANAPC1|MAD2L1|ANAPC2
51329 2,90E-11 6,99E-10 18 102 interphase of mitotic cell cycle CDKN1A|BLM|CDC7|CDC6|ANAPC10|POLA1|CCNB1|CDC23|CDK6|DBF4|POLD1|CDK2|MDM2|ANAPC4|ANAPC5|MNAT1|POLE|TAF1
51327 1,02E-07 1,44E-06 15 102 M phase of meiotic cell cycle UBE2B|RPA1|MRE11A|LIG3|RAD51B|MSH6|CCNA1|RAD50|RAD51C|RAD51|EXO1|CHEK1|CKS2|ATM|NBN
51321 1,18E-07 1,65E-06 15 103 meiotic cell cycle UBE2B|RPA1|MRE11A|LIG3|RAD51B|MSH6|CCNA1|RAD50|RAD51C|RAD51|EXO1|CHEK1|CKS2|ATM|NBN
10564 8,19E-06 9,75E-05 15 138 regulation of cell cycle process TIPIN|CREBBP|CDKN1A|UBE2B|MRE11A|CDC7|BRCA1|ANAPC10|MAD2L2|CCNB1|CDC23|CDC16|TIMELESS|MDM2|ATM
7093 2,08E-05 2,38E-04 10 52 mitotic cell cycle checkpoint MAD2L2|CCNA2|CDKN1A|CCNB1|CDK1|BUB1B|ATM|NBN|TP53|MAD2L1
7346 2,63E-05 2,95E-04 16 174 regulation of mitotic cell cycle CDKN1A|BUB1B|CDC6|ANAPC10|MAD2L2|CCNA2|CCNB1|CDC23|CDC16|CDK2|MDM2|CDK1|ATM|NBN|TP53|MAD2L1
86 9,00E-05 9,82E-04 7 21 G2/M transition of mitotic cell cycle CDKN1A|CCNB1|CDK2|ANAPC4|ANAPC5|ANAPC10|TAF1
#

total number of nodes in the gene ontology (GO) annotation;

*

number of nodes related to a given GO in the netwo