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. Author manuscript; available in PMC: 2021 Apr 1.
Published in final edited form as: Int Immunopharmacol. 2020 Mar 3;81:106359. doi: 10.1016/j.intimp.2020.106359

Fig. 6.

Fig. 6.

Sepsis decreases expression of α7nAChRs in mouse spleen but does not affect α4nAChRs. Spleens from Sham and CLP mice were collected at 8 or 16 h post-surgery. RNA from naïve control, sham, and CLP mouse spleens were evaluated by qPCR. A-C: Absolute amount of RNA. E-F: Relative expression – starting quantity of α7nAChR or α4nAChR mRNA was normalized to the geometric mean of the starting quantity for GAPDH and HPRT reference genes. These experiments were done using male C57BL/6J mice. Data in each panel were evaluated by one-way ANOVA, and post hoc comparisons were made using the Tukey test when overall group differences were detected. Group data are graphed as means ± SEM for the indicated n values. *P < 0.05 vs other groups.