Table 2. Relationship between clinicopathological characteristics of CRC patients and the Wnt inhibitory factor-1 (WIF-1) methylation status in the cancerous tissue.
| Clinicopathological features | Number (n = 50) |
WIF-1 methylation status in the cancerous tissue | ||
|---|---|---|---|---|
| Methylated n = 28 |
Unmethylated n = 22 |
p-value* | ||
| Age, mean ± SD, years | 60.4 ± 10.6 | 58.3 ± 12.6 | 0.535** | |
| Gender | 0.166 | |||
| Female/Male | 24/26 | 16/12 | 8/14 | |
| Tumor size, cm | 0.264 | |||
| ≤ 5 | 23 | 15 | 8 | |
| > 5 | 27 | 13 | 14 | |
| Grade | 0.107*** | |||
| I | 8 | 5 | 3 | |
| II | 34 | 16 | 18 | |
| III | 8 | 7 | 1 | |
| Tumor location | 0.009 | |||
| Left-sided | 27 | 20 | 7 | |
| Right-sided | 23 | 8 | 15 | |
| Stage | 0.999 | |||
| I–II | 17 | 10 | 7 | |
| III–IV | 33 | 18 | 15 | |
| Histological type | 0.479 | |||
| Mucinous | 10 | 7 | 3 | |
| Non-mucinous | 40 | 21 | 19 | |
| Lymph node metastasis | 0.153 | |||
| Positive | 25 | 11 | 14 | |
| Negative | 25 | 17 | 8 | |
*determined by Fisher’s exact test; **determined by Student’s t-test; ***determined by chi-square test.