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. 2020 Jun 25;19:151. doi: 10.1186/s12944-020-01329-0

Table 2.

Association between plasma ceramides and the severity of coronary stenosis after adjustment of multiple risk factors

Logistic Stepwise Regression Analyses Effect β P Odds Ratio 95% Confidence Interval
Model 1a Gender (male vs female) −0.472 0.001 2.57 1.446–4.567
HbA1c% 0.315 0.042 1.37 1.012–1.854
Cer (d18:0/24:1)/Cer (d18:0/24:0) 2.941 0.012 18.927 1.902–188.380
Diagnosis UAP vs atherosclerosis 0.733 0.069 62.903 19.586–202.016
Diagnosis AMI vs atherosclerosis 2.676 < 0.001 439.227 45.285- > 999.999
Model 2a Gender (male vs female) 0.480 0.003 2.609 1.401–4.859
Hypertension (yes vs. no) −0.235 0.121 0.625 0.346–1.131
HDL cholesterol −0.888 0.098 0.412 0.144–1.177
LDL cholesterol 0.467 0.03 1.579 1.046–2.384
HbA1c% 0.242 0.129 1.273 0.932–1.739
Cer (d18:0/24:1)/Cer (d18:0/24:0) 3.225 0.008 25.152 2.360–268.084
Diagnosis UAP vs atherosclerosis 0.806 0.049 70.024 21.017–233.300
Diagnosis AMI vs atherosclerosis 2.637 < 0.001 436.9.8 44.311- > 999.999

aadjustment factor.model 1: gender, age, smoking, prior MI/CI, current diagnosis, HbA1c%. model 2: gender, age, smoking, prior MI/CI, the presence of hypertension, current diagnosis, HbA1c%, TC, HDL-C, LDL-C. entry and exit criteria were 0.2 for stepwise selection