Table 2. Standard Gibbs Free Energy Change (ΔG_f^°) and Formation Constant (K_f, log K_f) for the Chelation of Cu(II) with AG (as per eq 11) in Aqueous Solution at 298.15 K^a.

complex [Cu(AG)x(H2O)n]2+	(kcal/mol)
[5] [Cu(AGA)(H2O)2]2+ (N1, N2)	–4.0	8.84 × 102	2.95
[6] [Cu(AGA)(H2O)3]2+ (N2)	–11.7	3.64 × 108	8.56
[7] [Cu(AGB)(H2O)2]2+ (N1, N4)	–3.9	6.95 × 102	2.84
[8] [Cu(AGB)(H2O)3]2+ (N2)	–10.6	5.76 × 107	7.76
[9] [Cu(AGC)(H2O)2]2+ (N1, N4)	–4.1	9.91 × 102	3.00
[10] [Cu(AGC)(H2O)3]2+ (N2)	–11.7	3.48 × 108	8.54
[11] [Cu(AGD)(H2O)2]2+ (N2, N4)	–21.9	1.10 × 1016	16.04
[12] [Cu(AGA)2]2+ (N1, N2)	–7.4	2.65 × 105	5.42
[13] [Cu(AGA)2]2+ (mirror im., N1, N2)	–7.1	1.48 × 105	5.17
[14] [Cu(AGA)2(H2O)2]2+ (N2)	–24.8	1.47 × 1018	18.17
[15] [Cu(AGB)2]2+ (N1, N4)	–7.6	3.53 × 105	5.55
[16] [Cu(AGB)2]2+ (mirror im., N1, N4)	–7.3	2.35 × 105	5.37
[17] [Cu(AGB)2(H2O)]2+ (N1, N4, N2′)	–15.8	3.98 × 1011	11.60
[18] [Cu(AGB)2(H2O)2]2+ (N2)	–24.1	4.82 × 1017	17.68
[19] [Cu(AGC)2]2+ (N1, N4)	–7.7	4.40 × 105	5.64
[20] [Cu(AGC)2]2+ (mirror im., N1, N4)	–7.5	3.12 × 105	5.49
[21] [Cu(AGC)2(H2O)]2+ (N1, N4, N2′)	–16.1	6.70 × 1011	11.83
[22] [Cu(AGC)2(H2O)2]2+ (N2)	–24.5	8.52 × 1017	17.93
[23] [Cu(AGD)2]2+ (N2, N4)	–40.8	8.24 × 1029	29.92
[24] [Cu(AGD)2]2+ (mirror im., N2, N4)	–40.9	9.91 × 1029	30.00
[25] [Cu(AGD)2(H2O)]2+ (N2)	–31.0	4.87 × 1022	22.69
[26] [Cu(AGD)2(H2O)2]2+ (N2)	–22.1	1.52 × 1016	16.18
[27] [Cu(AGA)(AGD)]2+ (N1, N2, N2′, N4)	–25.1	2.48 × 1018	18.39
[28] [Cu(AGB)(AGD)]2+ (N1, N4, N2′, N4)	–24.2	5.28 × 1017	17.72
[29] [Cu(AGC)(AGD)]2+ (N1, N4, N2′, N4)	–25.8	8.86 × 1018	18.95
[30] [Cu(AGC)(AGD)]2+ (mirror im., N1, N4, N2′, N4)	–24.4	7.58 × 1017	17.88

^aCoordinating atoms in the organic ligand are shown in parentheses for each complex; when two AGs are in different conformations or have different coordinating atoms, these are distinguished using a prime (′).