Table 1.
Demographic characteristics and laboratory values (mean ± SD or n (%)) at first physical activity assessment (stratified by physical activity level) for people living with HIV receiving care between January/2008 and July/2015.
| Variable | Total n=11,719 | Very Low n=3058 | Low n=4957 | Moderate n=2177 | High n=1527 | P valuea |
|---|---|---|---|---|---|---|
| Demographics | ||||||
| Age (yrs) | 43.8 ± 10.7 | 44.9 ± 10.2 | 43.7 ± 10.9 | 42.8 ± 10.5 | 43.1 ± 10.8 | < 0.01 |
| Birth Sex | ||||||
| Male | 9772 (83.4) | 2409 (24.7) | 4067 (41.6) | 1956 (20.0) | 1340 (13.7) | < 0.01 |
| Female | 1947 (16.6) | 649 (33.3) | 890 (45.7) | 221 (11.4) | 187 (9.6) | |
| Transgenderb | 0.04 | |||||
| Yes | 96 (1.3) | 37 (38.5) | 32 (33.3) | 18 (18.8) | 9 (9.4) | |
| No | 7104 (98.7) | 1842 (25.9) | 2863 (40.3) | 1445 (20.4) | 954 (13.4) | |
| Race | <0.01 | |||||
| % Black | 3917 (33.4) | 991 (25.3) | 1873 (47.8) | 586 (15.0) | 467 (11.9) | |
| % White | 6735 (57.5) | 1855 (27.5) | 2643 (39.2) | 1338 (19.9) | 899 (13.4) | |
| % Other | 1067 (9.1) | 212 (19.9) | 441 (41.3) | 253 (23.7) | 161 (15.1) | |
| % Hispanic ethnicity | 1597 (13.7) | 358 (11.8) | 666 (13.5) | 350 (16.2) | 223 (14.8) | < 0.01 |
| Body mass index | 26.5 ± 5.5 | 27.0 ± 6.3 | 26.5 ± 5.5 | 26.3 ± 4.8 | 26.0 ± 4.7 | < 0.01 |
| Health insurance | < 0.01 | |||||
| Uninsured | 1167 (9.9) | 279 (23.9) | 477 (40.9) | 240 (20.6) | 171 (14.6) | |
| Public | 6171 (52.7) | 1932 (31.3) | 2552 (41.3) | 1054 (17.1) | 633 (10.3) | |
| Private | 3083 (26.3) | 455 (14.8) | 1416 (45.9) | 643 (20.9) | 569 (18.4) | |
| Unknown | 1298 (11.1) | 392 (30.2) | 512 (39.5) | 240 (18.5) | 154 (11.8) | |
| Transmission Risk Factor | < 0.01 | |||||
| IVDU | 1771 (15.1) | 579 (32.7) | 697 (39.4) | 324 (18.3) | 171 (9.6) | |
| MSM | 6976 (59.5) | 1632 (23.4) | 2956 (42.4) | 1393 (19.9) | 995 (14.3) | |
| Heterosexual | 2615 (22.3) | 725 (27.7) | 1170 (44.7) | 402 (15.4) | 318 (12.2) | |
| Other/Unknown | 357 (3.1) | 122 (34.2) | 134 (37.5) | 58 (16.3) | 43 (12.0) | |
| Study Sitec | <0.01 | |||||
| UCSD | 3345 (28.6) | 908 (27.1) | 1351 (40.4) | 677 (20.3) | 409 (12.2) | |
| UAB | 2827 (24.1) | 728 (25.8) | 1358 (48.0) | 402 (14.2) | 339 (12.0) | |
| UW | 1697 (14.5) | 455 (26.8) | 704 (41.5) | 312 (18.4) | 226 (13.3) | |
| UCSF | 1093 (9.3) | 353 (32.3 0 | 432 (39.5) | 197 (18.0) | 111 (10.2) | |
| Fenway Health | 1028 (8.8) | 194 (18.9) | 359 (34.9) | 285 (27.7) | 190 (18.5) | |
| UNC | 918 (7.8) | 216 (23.5) | 383 (41.7) | 193 (21.0) | 126 (13.8) | |
| John Hopkins | 811 (6.9) | 204 (25.2) | 370 (45.6) | 111 (13.7) | 126 (15.5) | |
| Clinical and Laboratory Parameters | ||||||
| SBP (mmHg) | 125.9 ± 15.4 | 125.2 ± 15.9 | 126.0 ± 15.6 | 126.4 ± 14.9 | 126.3 ± 14.1 | < 0.01 |
| DBP (mmHg) | 78.7 ± 10.3 | 78.9 ± 10.5 | 78.9 ± 10.3 | 78.6 ± 10.2 | 78.2 ± 9.7 | 0.16 |
| Total Cholesterol (mg/dL) | 177.2 ± 42.7 | 176.4 ± 44.3 | 177.8 ± 43.3 | 177.5 ± 41.4 | 176.1 ± 39.2 | 0.60 |
| LDL-c (mg/dL) | 101.9 ± 33.7 | 100.6 ± 34.6 | 102.6 ± 33.4 | 102.4 ± 33.8 | 101.7 ± 32.6 | 0.20 |
| HDL-c (mg/dL) | 43.8 ± 16.4 | 41.7 ± 15.9 | 44.3 ± 16.2 | 44.3 ± 16.2 | 46.1 ± 17.7 | <0.01 |
| Triglycerides (mg/dL) | 176.5 ± 180.5 | 196.2 ± 174.0 | 176.3 ± 211.6 | 164.7 ± 131.2 | 154.0 ± 130.8 | <0.01 |
| Glucose (mg/mL) | 95.1 ± 30.9 | 97.8 ± 37.2 | 94.7 ± 30.2 | 94.2 ± 27.5 | 92.2 ± 22.9 | <0.01 |
| CD4+ T-cell count (cells/μl) | 506.7 ± 294.3 | 488.6 ± 315.7 | 508.7 ± 293.3 | 517.0 ± 275.0 | 521.9 ± 278.2 | < 0.01 |
| Plasma HIV RNA < 200 copies/ml | 7675 (70.5) | 1928 (68.5) | 3242 (70.1) | 1472 (72.6) | 1033 (72.5) | < 0.01 |
| d-drug exposure (ever) | 0.01 | |||||
| Yes | 2533 (21.6) | 724 (28.6) | 1031 (40.7) | 465 (18.4) | 313 (12.3) | |
| No | 9186 (78.4) | 2334 (25.4) | 3926 (42.7) | 1712 (18.7) | 1214 (13.2) | |
| Death during observation period | < 0.01 | |||||
| Yes | 510 (4.4) | 216 (42.4) | 204 (40.0) | 55 (10.8) | 35 (6.8) | |
| No | 11209 (95.6) | 2842 (25.4) | 4753 (42.4) | 2122 (18.9) | 1492 (13.3) | |
One-way ANOVA for continuous measures and chi-square for categorical measures
n(%) only for sites (UCSD, UAB, Fenway Health) collecting data on transgender identify up to 2015 (n=7,200)
Study Sites: UCSD = University of California, San Diego; UAB = University of Alabama at Birmingham; UW = University of Washington, Seattle; UCSF = University of San Francisco;UNC = University of North Carolina at Chapel Hill
Other = American Indian, Asian, Asian/Pacific Islander, Pacific Islander, Multiracial, Missing; IVDU = Intravenous drug use; MSM = Men having sex with men; d-drug = Didanosine, Stavudine, Zalcitabine
SBP = systolic blood pressure; DBP = diastolic blood pressure; LDL-c = low-density lipoprotein cholesterol; HDL-c = high-density lipoprotein cholesterol