Table 3. List of the Top 10 Hits and Known SphK1 Inhibitors, PF-543 and SKI-II, with Their Binding Affinity toward SphK1.

s. no.	compound ID	binding affinity (kcal/mol)
1	ZINC12898623	–12.2
2	ZINC02149103	–12.1
3	ZINC05434006	–12.0
4	ZINC04260971	–11.9
5	ZINC05433944	–11.9
6	ZINC03839231	–11.8
7	ZINC06623685	–11.8
8	ZINC08296863	–11.8
9	ZINC08788772	–11.8
10	ZINC12898106	–11.8
11	PF-543	–9.1
12	SKI-II	–8.8