Figure 4. Activation of group III mGluR attenuates GABAergic input to spinally projecting PVN neurons in WKY rats and SHRs.
A, Representative traces show the effect of L-AP4 on sIPSCs in labeled PVN neurons in one WKY rats and one SHR. B-E, Cumulative probability analyses show the effect of L-AP4 on the amplitude (B and C) and frequency (D and E) of sIPSCs in the above-labeled PVN neurons. F and G, Summary data show the effect of L-AP4 on the frequency (F) and amplitude (G) of sIPSCs of labeled PVN neurons in WKY rats and SHRs (n = 10 neurons from 4 rats in each group). *P < 0.05, compared with the baseline control. #P < 0.05, compared with the baseline in WKY rats.