TABLE 5.

Change in Scores Between Visits 2 and 3, by Patient-Rated Change Category

Change From Visit 2 to 3 in…	Much Better					Slightly Better—Much Worse
	n	Visit 2 Mean (SD)	Visit 3 Mean (SD)	Mean Change (SD)	SRM	n	Visit 2 Mean (SD)	Visit 3 Mean (SD)	Mean Change (SD)	SRM	P-Value*
PROMIS
Pain behavior	23	53.1 (7.0)	51.2 (8.9)	−1.9 (10.3)	−0.19	27	57.0 (6.8)	57.8 (5.6)	0.8 (7.9)	0.10	0.288
Pain interference	23	54.8 (8.4)	51.4 (7.7)	−3.4 (10.2)	−0.33	27	59.8 (7.4)	59.4 (8.0)	−0.5 (8.1)	−0.06	0.268
Physical function	23	40.8 (9.0)	44.3 (4.9)	3.5 (8.8)	0.40	27	35.6 (7.1)	38.0 (4.2)	2.4 (5.7)	0.43	0.604
SF-12
PCS	23	41.1 (9.2)	46.2 (6.5)	5.0 (7.8)	0.65	27	35.7 (10.3)	36.9 (6.8)	1.1 (10.6)	0.11	0.149
MCS	23	48.5 (12.8)	54.4 (9.9)	5.8 (10.8)	0.54	27	48.4 (12.6)	48.8 (10.1)	0.4 (11.2)	0.04	0.091
ODI	22	26.0 (15.6)	15.8 (10.2)	−10.2 (13.4)	−0.76	26	40.1 (17.9)	32.2 (12.9)	−7.9 (18.2)	−0.44	0.629
Zurich
Pain	23	2.23 (0.81)	2.06 (0.55)	−0.22 (0.80)	−0.28	26	3.22 (0.73)	3.03 (0.71)	−0.19 (0.69)	−0.28	0.907
Neuroischemic	23	1.91 (0.69)	1.71 (0.83)	−0.21 (0.65)	−0.32	27	2.31 (0.89)	2.41 (0.80)	0.09 (0.69)	0.13	0.124
Symptom severity	23	2.07 (0.46)	1.86 (0.51)	−0.21 (0.48)	−0.44	27	2.68 (0.72)	2.66 (0.66)	−0.02 (0.46)	−0.04	0.155
Physical function	23	1.76 (0.56)	1.49 (0.43)	−0.27 (0.52)	−0.52	27	2.21 (0.68)	1.99 (0.59)	−0.22 (0.60)	−0.37	0.770

SRM, standardized response mean = mean change/SD.

^*P-value is comparing mean change scores between the two groups.

MCS indicates mental component score; ODI, Oswestry disability index; PCS, physical component score; PROMIS, patient reported outcomes measurement information system; SD, standard deviation; SF-12, Short-Form 12.