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Biological Activities of Anaephene A (1), Anaephene B (2), and Anaephene C (3)
| Antibacterial and Antifungal Activities (MIC in μg/mL) | Cytotoxicity (IC50 in μM) | |||||||
|---|---|---|---|---|---|---|---|---|
| Compound | B. cereus | S. aureus | P. aeruginosa | M. tuberculosis | S. cerevisiae | HCT116 | MDA-MB-231 | A549 |
| 1 | 11 | 22 | >22 | >22 | >22 | 26 | 37 | 27 |
| 2 | 6.1 | 6.1 | >24 | >24 | >24 | 71 | 28 | 33 |
| 3 | 22 | 22 | >22 | >22 | >22 | >100 | 49 | 42 |
| Ciprofloxacin | 0.03 | |||||||
| Chloramphenicol | 4.0 | |||||||
| Streptomycin | 6.2 | 3.1 | ||||||
| Nystatin | 23 | |||||||
