Table 3.
Clinical outcome and duration of viral shedding from illness onset for the 3 patient groups with COVID-19
| First generation (n = 83) | Second generation (n = 44) | Third generation (n = 44) | Total (n = 171) | p | |
|---|---|---|---|---|---|
| Severe illnessa,b | 27 (32.5) | 12 (27.3) | 32 (72.7) | 71 (41.5) | <0.001 |
| Time from illness onset to severe illness (days) | 8.0 (6.0, 10.0) | 8.0 (6.0, 11.0) | 7.5 (6.0, 9.25) | 8.0 (6.0, 10.0) | 0.501 |
| Critical illness)a,b | 9 (10.8) | 3 (6.8) | 17 (38.6) | 29 (17.0) | <0.001 |
| Time from illness onset to critical illness (days) | 10.1 ± 2.1 | 9.0 ± 4.6 | 8.6 ± 3.7 | 9.1 ± 3.4 | 0.561 |
| Intubationa,b | 3 (3.6) | 1 (2.3) | 9 (20.5) | 13 (7.6) | 0.002 |
| Time from illness onset to intubation (days) | 9.5 ± 2.1 | 10.0 | 8.6 ± 2.9 | 8.8 ± 2.6 | 0.836 |
| Extracorporeal membrane oxygenation (ECMO) | 3 (3.6) | 1 (2.3) | 5 (11.4) | 9 (5.3) | 0.135 |
| Time from illness onset to ECMO (days) | 18.0 ± 9.9 | 29.0 | 19.2 ± 6.1 | 20.1 ± 7.0 | 0.453 |
| Duration of viral shedding from illness onset (days) | 17.0 (11.0, 24.0) | 16.5 (12.3, 20.8) | 18.0 (13, 26.5) | 17.0 (12.0, 24.0) | 0.706 |
Data are presented as n (%) unless stated otherwise. ECMO, extracorporeal membrane oxygenation.
ap Value between groups 2 and 3 0 < .05.
bp Value between groups 1 and 3 < 0.05.
These bold values represent P<0.05.