Table 3. Effect of MEAA on biochemical indices of the treated and untreated rats.
Treatment dose | ALT (U/L) | ALP (U/L) | AST (U/L) | Cr (µmol/L) | Urea (µmol/L) | Uric acid(µmol/L) | Total protein(gm/L) |
---|---|---|---|---|---|---|---|
Control 5.0 ml DW | 63.30 ± 0.33 | 158.00 ± 5.29 | 131.33 ± 13.90 | 22.66 ± 0.33 | 7.03 ± 0.20 | 115.66 ± 40.37 | 58.33 ± 3.38 |
5.0 mg/kgBW MEAA | 72.50 ± 2.59 | 156.00 ± 6.92 | 212.00 ± 50.80 | 23.00 ± 0.57 | 7.05 ± 0.28 | 96.00 ± 31.75 | 56.33 ± 1.15 |
50 mg/kgBW MEAA | 71.66 ± 6.83 | 209.66 ± 33.38 | 144.00 ± 24.24 | 22.33 ± 0.33 | 6.83 ± 0.38 | 62.00 ± 4.04 | 57.66 ± 0.88 |
300 mg/kgBW MEAA | 69.33 ± 5.45 | 169.00 ± 12.22 | 131.00 ± 35.11 | 23.00 ± 0.57 | 6.53 ± 0.37 | 66.00 ± 17.69 | 59.33 ± 2.02 |
2,000 mg/kgBW MEAA | 57.66 ± 5.54 | 172.33 ± 3.75 | 104.00 ± 16.44 | 22.33 ± 0.88 | 6.267 ± 0.26 | 53.33 ± 6.69 | 58.33 ± 1.20 |
Notes.
Values represent mean ± SEM, n = 3. Kruskal–Walis test was used to analyse the data and P < 0.05 was considered as statistically significant.
- ALT
- Alanine aminotransaminase
- ALP
- Alkaline phosphatase
- AST
- Aspartate aminotransferase
- Cr
- Creatinine
- MEAA
- methanolic extract of Asparagus africanus