Table 4. Effect of MEAA on haematological parameters of the treated and untreated rats.
| Treatment dose | HGB (g/L) | HCT (L/L) | RBC (1012/L) | MCV (fl) | MCH (pg) | MCHC (g/L) | RDW (%) | WBC (109/L) | Platelet (109/L) |
|---|---|---|---|---|---|---|---|---|---|
| Control 5.0 ml Dil H2O | 137.00 ± 1.0 | 0.44 ± 0.01 | 6.93 ± 0.01 | 64.33 ± 1.15 | 19.8 ± 0.1 | 303.67 ± 0.57 | 12.33 ± 0.15 | 10.10 ± 0.1 | 756 ± 1.0 |
| 5.0 mg/kgBW MEAA | 136.67 ± 1.15 | 0.44 ± 0.01 | 6.66 ± 0.09a | 64.67 ± 0.58 | 19.87 ± 0.58 | 311.33 ± 1.15* | 12.2 ± 0.17 | 11.13 ± 0.12** | 564.67 ± 0.58 |
| 50 mg/kgBW MEAA | 139.67 ± 4.73 | 0.44 ± 0.01 | 7.02 ± 0.32 | 62.0 ± 1.0 | 19.6 ± 0.2 | 318.33 ± 3.51* | 11.73 ± 0.32a | 12.00 ± 0.7** | 977.67 ± 87.39** |
| 300 mg/kgBW MEAA | 143.33 ± 2.52a | 0.44 ± 0.02 | 7.44 ± 0.04a | 63.67 ± 1.53 | 19.33 ± 0.15 | 313.66 ± 1.53* | 12.5 ± 0.2 | 11.23 ± 0.15** | 1,014 ± 2.0** |
| 2,000 mg/kgBW MEAA | 132.0 ± 5.57a | 0.42 ± 0.02 | 6.71 ± 0.53 | 61.0 ± 2.0 | 19.4 ± 0.43 | 312 ± 1.73* | 11.6 ± 0.61a | 8.33 ± 0.21** | 817.67 ± 156.86 |
Notes.
Values are expressed as mean ± SEM, n = 3. One-way ANOVA was used to analyse the data and P < 0.05 was considered as statistically significant. Tukey HSD post-hoc test was further used to precisely determine the actual significance between groups.
- RBC
- Red Blood Cell
- WBC
- White Blood Cell
- PCV
- Pack Cell Volume
- MCV
- Mean Corpuscular Volume
- MCH
- Mean Corpuscular Haemoglobin
- MCHC
- Mean Corpuscular Haemoglobin Concentration
- HCT
- Haematocrit
- RDW
- Red Cell Distribution Width
- PLT
- platelet Count
- MEAA
- methanolic extract of Asparagus africanus
- MAA
- methanolic extract of A. africanus
*
p < 0.05 significantly different from control.
**
p > 0.001 significantly different from control.
a
p < 0.05 significantly different from each other in a column.