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. Author manuscript; available in PMC: 2021 Jul 1.

Published in final edited form as: Lung Cancer. 2020 Apr 30;145:132–139. doi: 10.1016/j.lungcan.2020.03.023

Table 4.

Logistic Regression for the association between Radiation Pneumonitis grades and Radiographic Characteristics

	Grade 3–5 RP vs. Grade 2 RP		Lethal RP vs. Non-Lethal RP
	OR³ (95% CI)	p-value	OR³ (95% CI)	p-value
Extent^*		0.002		0.01
<10	Ref.		Ref.
≥10	5.22 (1.83, 14.9)		16.50 (1.87, 145.61)
Distribution		0.0004		0.0003
Not Diffuse	Ref.		Ref.
Diffuse	20.07 (3.87, 104.1)		28.75 (4.57, 180.99)
Bilateral		0.12		0.16
No	Ref.		Ref.
Yes	2.33 (0.80, 6.78)		4.71 (0.54, 41.11)
All Lobes		0.07		0.02
No	Ref.		Ref.
Yes	2.53 (0.92, 6.92)		14.45 (1.64, 127.14)
Out of Field		0.51
No	Ref.		-	-
Yes	1.58 (0.40, 6.24)		-	-
Pattern		0.0009		0.0002
AIP/ARDS pattern	16.57 (3.16, 86.74)		35.0 (5.37, 228.04)
Other patterns	Ref.		Ref.

RP – radiation pneumonitis, OR – odds ratio, CI – confidence interval, AIP/ARDS – acute interstitial pneumonia/acute respiratory distress syndrome

^*

Extent was obtained for each patient as the sum of the scores in the upper, and middle, and lower lungs.