Table 2.

Age-Specific Prevalence of Vascular Disease

	Age Decade, yb
Cerebrovascular Pathologic Evaluation	50–59	60–69	70–79	80–89
All Patients, Prevalence (95% CI)
WMH	—	5.2 (3.0–7.3)	16.5 (12.4–20.7)	47.5 (38.5–56.6)
Total CMB	7.0 (4.0–10.1)	10.3 (7.3–13.3)	18.8 (14.6–23.1)	34.8 (26.9–42.7)
Deep CMB	0.2 (0.0–0.7)	2.2 (0.7–3.6)	5.2 (2.9–7.5)	8.1 (3.2–13.0)
Lobar CMB	6.6 (3.7–9.6)	8.0 (5.3–10.6)	15.3 (11.4–19.2)	27.3 (20.2–34.3)
Total infarct	2.7 (0.9–4.4)	8.5 (5.8–11.1)	17.3 (13.2–21.4)	39.8 (30.5–49.1)
Lacunar infarct	1.7 (0.3–3.1)	6.7 (4.4–9.0)	11.3 (8.1–14.5)	26.1 (18.3–33.9)
Cortical infarct	0.6 (0.0–1.5)	2.1 (1.0–3.3)	6.0 (3.3–8.6)	18.4 (8.5–28.2)
Men, Prevalence (95% CI)
WMH	—	4.5 (1.9–7.0)	11.2 (6.8–15.7)	50.0 (37.0–63.1)
Total CMB	8.5 (3.8–13.2)	15.1 (9.9–20.2)	22.3 (16.1–28.6)	37.7 (26.5–49.0)
Deep CMB	0.5 (0.0–1.4)	3.3 (0.5–6.1)	5.4 (2.2–8.6)	6.2 (1.7–10.7)
Lobar CMB	8.5 (3.8–13.2)	12.0 (7.4–16.7)	19.5 (13.6–25.5)	30.5 (20.8–40.3)
Total infarct	4.3 (1.1–7.5)	10.7 (6.8–14.5)	21.3 (15.2–27.3)	46.7 (33.1–60.2)
Lacunar infarct	2.3 (0.0–4.7)	9.1 (5.5–12.8)	16.5 (11.0–22.0)	28.4 (16.3–40.4)
Cortical infarct	1.3 (0.0–3.2)	3.0 (1.0–5.0)	7.1 (3.5–10.7)	27.3 (10.4–44.2)
Women, Prevalence (95% CI)
WMH	—	5.8 (2.4–9.1)	21.0 (14.3–27.7)	45.1 (32.8–57.4)
Total CMB	5.7 (1.7–9.7)	6.2 (2.9–9.6)	15.9 (10.1–21.7)	32.0 (20.1–43.8)
Deep CMB	—	1.2 (0.0–2.4)	5.1 (1.8–8.4)	9.9 (1.4–18.4)
Lobar CMB	5.0 (1.2–8.7)	4.5 (1.7–7.2)	11.7 (6.5–17.0)	24.1 (13.5–34.6)
Total infarct	1.2 (0.0–2.8)	6.6 (2.9–10.3)	14.0 (8.3–19.6)	32.8 (21.5–44.0)
Lacunar infarct	1.2 (0.0–2.8)	4.5 (1.6–7.5)	6.9 (3.1–10.7)	28.4 (16.3–40.4)
Cortical infarct	—	1.4 (0.0–2.8)	5.0 (1.1–8.9)	9.7 (2.5–16.8)

^aAbbreviations: CI= confidence interval; CMB=cerebral microbleed; WMH=white-matter hyperintensity.

^bDash indicates no data available.