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Healthy obese adults without type 2 diabetes were screened for eligibility in the trial and 40 were randomized to empagliflozin/matching placebo. Four participants did not return for follow-up procedures and 1 participant was excluded immediately after randomization due to diagnosis of type 2 diabetes. 35 participants (18 empagliflozin/17 matching placebo) had full data available for the modified intention-to-treat analysis.
