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. 2020 Jun 25;15(6):e0232381. doi: 10.1371/journal.pone.0232381

Fig 8. Raised ICP in alphavirus encephalitis.

Fig 8

A) ICP time series in a mock-infected macaque, superimposed on temperature curve. B) EEEV-infected macaques typically exhibit the largest ICP increases during the febrile period; an example ICP trace from a representative macaque (3–19) is superimposed upon temperature helps to illustrate the rise in ICP in relation to the fever curve. C) Similarly, in a representative VEEV-infected macaque (115–18), intracranial pressure rises after the onset of a characteristic biphasic fever. Temperature curves comprise gray traces.