Table 3. Number of search results of adverse drug reactions (ADRs) and anaphylaxis and hypersensitivity cases due to an excipient in a biologic formulation.

	Number of Search Results
Excipient Class and Name	Adverse Drug Reaction or Adverse Effect	Anaphylaxis or Allergic Reaction
Surfactant or Polysorbate	3	6
By Excipient Name polysorbate 80, polysorbate 20, poloxamer 188	1	2
Sugar or Polyol	4	4
By Excipient Name sucrose, mannitol, sorbitol, trehalose, lactose, glycerol or glycerin	9	17
Preservative	0	0
By Excipient Name citric acid, metacresol, phenol, zinc, methionine, glutathione, benzyl alcohol, edetate disodium	11	17