Skip to main content
. 2020 Jun 25;15(6):e0235218. doi: 10.1371/journal.pone.0235218

Table 3. Most highly enriched KEGG pathways of DEGs between Holstein steers and bulls.

KEGG Terms Input number P-Value Gene name
Tight junction (cell polarity; muscle cell development) 3 0.006 MYH4, MYH1, MYH10
GABAergic synapse 2 0.025 SLC6A1, PLCL1
Synthesis and degradation of ketone bodies (ketone bodies degraded to acetyl-CoA for fatty acids synthesis) 1 0.032 BDH1
Oxytocin signaling pathway (cell proliferation; contraction) 2 0.067 ROCK2, CDKN1A
Butanoate metabolism (Acetyl-CoA for fatty acids synthesis) 1 0.076 BDH1
Purine metabolism 2 0.086 ENSBTAG00000045889 (pseudogene), AMPD1
Galactose metabolism (glycerol for fatty acids synthesis) 1 0.087 GANC
Linoleic acid metabolism (fatty acid metabolism) 1 0.094 CYP2R1
Pyruvate metabolism (linked to fatty acid biosynthesis through Malonyl-CoA 1 0.101 ME2
Bladder cancer (X) 1 0.101 CDKN1A
Proteoglycans in cancer (cell growth) 2 0.107 ROCK2, CDKN1A
Metabolic pathways 6 0.125 ALDH1A1, AMPD1, ENSBTAG00000045889 (pseudogene), GANC, CYP2R1, BDH1