Fig 1. A subset of P3HR1 strain EBV-infected CBH mice develop tumors.

Kaplan-Meier analysis was performed comparing tumor development over time (tumor incidence curve) in CBH mice infected with P3HR1 (EBNA2-deleted) virus versus B95.8 (WT, EBNA2-sufficient) virus. B95.8 data was previously published [44]. P3HR1 infected mice were infected with a 25- to 50-fold higher dose of virus compared to B95.8 infected mice as described in the methods. Log-Rank test was performed on tumor incidence curves.