Table 2. Hazard ratios for the association of baseline variables with hazard of death.
Group | Variable1 | HR2 | 95%CI | HR3 | 95%CI | HR4 | 95%CI |
---|---|---|---|---|---|---|---|
Demographic variables | Male | 1.34 | 0.80–2.27 | ||||
Age1 | 1.09 | 1.07–1.12 | 1.09 | 1.07–1.11 | 1.03 | 1.01–1.06 | |
Retirement home | 1.19 | 0.64–2.22 | |||||
Comorbidities and medications on admission | BADL dependence | 2.98 | 1.57–5.64 | 2.51 | 1.38–3.94 | ||
Hypertension | 1.48 | 0.80–2.71 | |||||
Diabetes mellitus | 2.55 | 1.53–4.26 | 2.33 | 1.38–3.94 | 2.42 | 1.43–4.09 | |
Prior lung disease | 0.93 | 0.52–1.64 | |||||
Chronic kidney failure | 0.97 | 0.51–1.83 | |||||
Cardiovascular disease | 1.93 | 1.08–3.46 | |||||
Multiple medications | 1.57 | 0.90–2.74 | |||||
Symptoms on admission | Low-grade fever | 0.61 | 0.32–1.16 | ||||
Cough | 1.40 | 0.69–2.84 | |||||
Productive cough | 1.02 | 0.57–1.80 | |||||
Haemoptysis | 0.94 | 0.13–6.84 | |||||
Dyspnoea | 1.64 | 0.94–2.84 | |||||
Anosmia | 0.26 | 0.06–1.09 | |||||
Ageusia | 0.11 | 0.02–0.83 | 0.11 | 0.02–0.83 | |||
Headache | 1.25 | 0.40–3.88 | |||||
Nausea | 0.64 | 0.28–1.44 | |||||
Muscle tiredness | 0.75 | 0.45–1.26 | |||||
Myalgia | 0.60 | 0.33–1.09 | |||||
Odynophagia | 1.73 | 0.74–4.04 | |||||
Diarrhoea | 0.57 | 0.27–1.22 | |||||
General malaise | 1.28 | 0.74–2.21 | |||||
Gastrointestinal symptoms | 0.58 | 0.29–1.16 | |||||
Fatigue | 0.76 | 0.46–1.26 | |||||
Duration of symptoms (days)1 | 0.98 | 0.91–1.05 | |||||
Physical exam on admission | Fever | 2.00 | 1.11–3.60 | ||||
Baseline SatO21 | 0.93 | 0.91–0.95 | |||||
Need for O2 | 5.17 | 2.35–11.41 | |||||
FiO21 | 1.05 | 1.03–1.07 | |||||
SatO2/FiO21 | 0.43 | 0.33–0.56 | 0.44 | 0.34–0.58 | 0.57 | 0.43–0.77 | |
X-Ray findings on admission | Opacities | 2.93 | 1.24–6.92 | ||||
Interstitial opacities | 2.37 | 1.28–4.40 | 2.36 | 1.24–4.49 | |||
Hilar congestion | 1.28 | 0.71–2.32 | |||||
Pleural effusion | 1.21 | 0.60–2.43 |
1 Quantitative variables. Hazard ratios are expressed as increments in the hazard of death per unit increase in the variable. For dichotomous variables, the reference category was No or Absent.
2 Hazard ratios adjusted by age.
3 Hazard ratios obtained with stepwise regression models including age and the remaining variables in each group.
4 Hazard ratios obtained with a stepwise regression model including all variables retained in the models fitted for each group of variables.
BADL, Basic activities of daily living.