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. Author manuscript; available in PMC: 2020 Jun 25.
Published in final edited form as: Blood Rev. 2010 Feb 11;24(2):69–82. doi: 10.1016/j.blre.2010.01.001

Fig. 6.

Fig. 6.

Histone deacetylase inhibitors can induce transformed cell growth arrest and death by different pathways. HDACs – histone deacetylases; HIF-1α – hypoxia induced factor-1α; HSP90 – heat shock protein 90; PP1 – protein phosphatase; ROS – reactive oxygen species; TBP2 – thioredoxin binding protein 2; Trx – thioredoxin; VEGF – vascular endothelial growth factor.