Skip to main content
. Author manuscript; available in PMC: 2020 Jun 25.
Published in final edited form as: Eur J Cell Biol. 2010 Apr 1;89(7):564–573. doi: 10.1016/j.ejcb.2009.11.029

Fig. 4. CREB binding to cFos promoter was inhibited by NSC13746 and not affected by NSC13782.

Fig. 4.

Cells were treated for 24 h with 100 μM of drug and lipofectamine or mock treated with lipofectamine only. Chromatin immunoprecipitation was used to detect CREB binding to cFos promoter in cells treated with NSC13746, NSC13782 or mock treated. Normalization to input level produced 30% lower level of band intensities in NSC13746 treated cells in comparison with mock treated cells indicating reduction of CREB binding. Treatment of cells with NSC13782 does not affect CREB binding.