Table I.
Baseline characteristics of the women with PCOS enrolled in the study.
| Subject | Age (years) | BMI (kg/m2) | Months since LMP | LH (IU/l) | FSH (IU/l) | Oestradiol (pmol/l) | Testosterone (nmol/l) | FAI | PCOS phenotype |
|---|---|---|---|---|---|---|---|---|---|
| 1 | 31 | 38 | 7 | 17.9 | 6.6 | 241 | 1.9 | 7.9 | B |
| 2 | 30 | 30 | 2 | 11.6 | 5.8 | 95 | 0.9 | 7.5 | A |
| 3 | 30 | 44 | 14 | 16.4 | 6.9 | 218 | 1.8 | 18 | A |
| 4 | 24 | 40 | 8 | 6.7 | 4.9 | 180 | 1.9 | 9.5 | A |
| 5 | 19 | 35 | 3 | 15.9 | 6.9 | 250 | 2.4 | 7.3 | B |
| 6 | 30 | 20 | 2 | 12 | 3 | 273 | 1.8 | 1.9 | A |
| 7 | 21 | 38 | 2 | 9.7 | 3.8 | 265 | 1.1 | 4.2 | D |
| 8 | 26 | 33 | 5 | 7.8 | 3.9 | 152 | 2.4 | 6.9 | B |
| 9 | 28 | 36 | 3 | 6.1 | 3.2 | 126 | 1.3 | 8.7 | A |
| 10 | 27 | 34 | 12 | 5.7 | 3.9 | 167 | 1 | 6.3 | B |
| Mean ± SEM | 27 ± 1.3 | 35 ± 2.1 | 6 ± 1.4 | 11.0 ± 0.4 | 4.9 ± 0.5 | 197 ± 19.5 | 1.7 ± 0.2 | 7.8 ± 1.3 |
All women were oligo/amenorrhoeic. Phenotype A = oligo/amenorrhoea, clinical or biochemical hyperandrogenism and polycystic ovaries; Phenotype B = oligo/amenorrhoea and hyperandrogenism; Phenotype D = oligo/amenorrhoea and polycystic ovaries. Reference range for testosterone, 0.3–1.9 nmol/l, and for FAI (free androgen index), <6.5.
FAI, free androgen index; LMP, last menstrual period; NK3Ra, neurokinin 3 receptor antagonist; PCOS, polycystic ovary syndrome.