Table 1.
Demographics, clinical characteristics on admission, treatment, and outcomes of three patients with COVID‐19.
| Variables | Patient 1 | Patient 2 | Patient 3 |
|---|---|---|---|
| Demographics | |||
| Age | 47 | 62 | 52 |
| Gender | Female | Male | Female |
| Comorbidities | None | None | Hypertension |
| Smoking status | Lifelong non‐smoker | Smoker | Lifelong non‐smoker |
| Days from testing positive to admission | 2 | 5 | 6 |
| Clinical findings on presentation | |||
| Temperature (°C) | 36.9 | 37 | 37 |
| Respiratory rate (bpm) | 16 | 20 | 16 |
| O2 saturation (in room air, %) | 99 | 95 | 99 |
| Blood pressure (mmHg) | 108/64 | 147/87 | 163/97 |
| Heart rate (bpm) | 96 | 105 | 110 |
| MEWS | 1 | 2 | 1 |
| Laboratory results | |||
| Total white cell count (×109/L) | 5.1 | 8.0 | 5.1 |
| Absolute lymphocyte count (×109/L) | 2.2 | 2.3 | 2.1 |
| Absolute monocyte count (×109/L) | 0.4 | 1.2 | 0.5 |
| Absolute neutrophil count (×109/L) | 2.4 | 4.4 | 2.4 |
| Platelet (×109/L) | 285 | 467 | 414 |
| LDH (U/L) | 335 | 349 | 306 |
| C‐reactive protein (mg/dL) | 0.21 | 1.57 | 2.13 |
| D‐dimer (ng/mL) | 0.28 | 0.27 | 1.89 |
| Ferritin (μg/mL) | 182.72 | — | 103.67 |
| Fibrinogen (g/L) | 2.5 | 5.7 | 2.7 |
| Procalcitonin (ng/dL) | <0.02 | <0.02 | <0.02 |
| Radiological imaging | |||
| Chest radiograph | Left upper zone peripheral consolidation | Left upper zone peripheral consolidation | Air space opacities in the right lower zone |
| HRCT | Bilateral lower zone peripheral GGOs | Peripheral GGOs involving both the left upper and right lower lobes | Bilateral lower zone peripheral GGOs |
| Treatment and outcome | |||
| Drug therapy | HCQ | HCQ | HCQ |
| 400 mg bd Day 1 | 400 mg bd Day 1 | 400 mg bd Day 1 | |
| 200 mg bd Days 2–10 azithromycin | 200 mg bd Days 2–5 azithromycin | 200 mg bd Days 2–10 azithromycin | |
| 500 mg od Day 1 | 500 mg od Day 1 | 500 mg od Day 1 | |
| 250 mg od Days 2–5 lopinavir/ritonavir | 250 mg od Days 2–5 | 250 mg od Days 2–5 | |
| 400/100 mg bd Days 1–10 | |||
| Length of hospital stay (days) | 14 | 10 | 16 |
| Repeated COVID‐19 RT‐PCR test | Positive at day 10. Negative at days 13 and 14 | Negative at days 10 and 13 | Negative at days 10 and 13 |
bd, Twice daily; bpm, breaths per minute; COVID‐19, 2019‐novel coronavirus; GGO, ground‐glass opacification; HCQ, hydroxychloroquine; HRCT, high‐resolution computed tomography; LDH, lactate dehydrogenase; MEWS, Modified Early Warning Score; RT‐PCR, reverse transcription‐polymerase chain reaction.