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. Author manuscript; available in PMC: 2021 Jul 1.
Published in final edited form as: Brain Behav Immun. 2020 Mar 5;87:715–724. doi: 10.1016/j.bbi.2020.03.002

Figure 1: Psychological symptoms and blood biomarkers.

Figure 1:

Shown are the mean Brief Symptom Inventory-18 Global Severity Index (BSI-GSI) scores along with a priori (top row) and secondary biomarkers (bottom rows) at the preseason baseline (BL), early-acute (EA), late-acute (LA), 8 day (8d), 15 day (15d), and 45 day (45d) visits in athletes with sport-related concussion (SRC), contact sport controls (CC), and non-contact sport controls (NCC). Error bars are the standard error of the mean. KynA = kynurenic acid, 3HK = 3-hydroxykynurenine, QuinA = quinolinic acid, KYN = kynurenine, TRP = tryptophan, CRP = c-reactive protein, pg/mL = picogram per milliliter, nM = nanomolar, uM = micromolar. Natural log (ln) transformed biomarker values are shown. Letters indicate post-hoc comparisons: ‘a’ = SRC: LA > BL, 8d, 15d, 45d; ‘b’ = LA: SRC > CC, NCC; ‘c’ = SRC: EA > BL, 8d, 45d, ‘d’ = SRC, CC > NCC. The complete list of post-hoc comparisons is provided in the text.