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. Author manuscript; available in PMC: 2020 Nov 4.
Published in final edited form as: Nat Immunol. 2020 May 4;21(7):736–745. doi: 10.1038/s41590-020-0669-6

Extended Data Fig. 7. Disulfiram protects against LPS-induced sepsis.

Extended Data Fig. 7

(a-c) Mice were pretreated with disulfiram (50 mg/kg) or vehicle (Ctrl) by intraperitoneal injection 24 and 4 hrs before intraperitoneal challenge with 15 mg/kg LPS and followed for survival. Serum IL-1β (a), TNF (b) and IL-6 (c) were measured by multiplex luminex assay (n= 5/group) 12 hrs post LPS challenge. Shown are mean ± s.e.m. Statistical differences between the groups were calculated by multiple t-test. Type I error was corrected by the Holm-Sidak method.