Table 3. Selected genes with differential methylation and relative location of these CpG sites in the genes.
| Probe ID | Gene | Description | ∆β in array | p in array | ∆β in validation | p in validation | Location in gene |
|---|---|---|---|---|---|---|---|
| cg13078798 |
TGFBR3 |
Transforming growth factor, β receptor III |
0.54 |
2.17E-07 |
−0.08 |
0.376 |
Body |
| cg16055869 |
CXCL5 |
Chemokine (C-X-C motif) ligand 5 |
0.24 |
4.58E-06 |
0.08 |
0.138 |
TSS200 |
| cg21951797 |
TNXB |
Tenascin XB |
0.47 |
7.13E-06 |
0.06 |
0.002 |
Body |
| cg07139946 |
−0.18 |
1.42E-06 |
0.17 |
0.16 |
|||
| cg15724328 |
ANGPT1 |
Angiopoietin 1 |
−0.31 |
5.76E-06 |
N/A* |
|
Body |
| cg17982478 |
PLEKHA7 |
Pleckstrin homology domain contaning, family A member 7 |
0.36 |
5.35E-07 |
0.005 |
0.42 |
TSS1500 |
| cg04827020 |
THBS1 |
Thrombospondin 1 |
0.27 |
1.74E-06 |
N/A* |
|
Body |
| cg16933229 |
PITX2 |
Paired–like homeodomain 2 |
0.6 |
3.72E-07 |
N/A* |
|
|
| cg03133735 |
0.6 |
1.17E-07 |
0.02 |
0.001 |
|
||
| cg01733176 |
0.38 |
1.34E-08 |
0.1 |
0.06 |
|
||
| cg26500914 |
DAXX |
Death-domain associated protein |
0.5 |
4.11E-06 |
0.32 |
0.08 |
Body |
| cg24498636 |
0.48 |
2.26E-06 |
0.32 |
0.08 |
|||
| cg05431670 |
0.28 |
2.37E-09 |
0.07 |
0.001 |
TSS200 |
||
| cg16277169 |
TBX3 |
T-Box 3 |
−0.32 |
1.10E-07 |
−0.56 |
0.04 |
Body |
| cg18161956 |
−0.44 |
4.25E-08 |
−0.14 |
0.734 |
|||
| cg09413529 |
−0.49 |
7.55E-06 |
−0.82 |
0.001 |
|||
| cg11246938 |
−0.39 |
5.36E-08 |
−0.19 |
0.051 |
|||
| cg09053536 |
−0.51 |
7.33E-06 |
−0.89 |
0.001 |
|||
| cg13661397 | NET1 | Neuroepithelial cell transforming 1 | 0.47 | 8.37E-10 | −0.00043 | 0.861 | TSS200 |
* Not available due to shortage of sites for methylation sensitive restriction enzyme. TSS200: 200 base pairs upstream of the transcription start site; TSS1500: 1500 base pairs upstream of the transcription start site.