Table 6. Comparison of numerical areal densities (NA) of inflammatory cells in FVMs of patients with acitve PDR and patients with inactive PDR – median (minimum-maximum); Mann–Whitney test.
| Numerical areal density (NA) | PDR (n=33) | active PDR (n=25) | inactive PDR (n=8) | P value |
|---|---|---|---|---|
| NA of CD45+ cells per mm2 |
237.31 (0–1253.99) |
237.31 (38.80–1253.99) |
205.03 (0–442.07) |
0.27 |
| NA of CD3+ cells per mm2 |
22.86 (0–178.57) |
45.45 (10.85–178.57) |
12.17 (0–22.86) |
0.008 |
| NA of CD4+ cells per mm2 |
39.37 (0–535.71) |
90.85 (6.51–535.71) |
21.51 (0–31.25) |
0.003 |
| NA of CD8+ cells per mm2 |
35.24 (0–408.65) |
35.24 (0–408.65) |
30.27 (0–64.58) |
0.16 |
| NA of CD19+ cells per mm2 |
4.34 (0–115.27) |
11.16 (0–115.27) |
0 (0–0) |
0.001 |
| NA of CD14+ cells per mm2 | 216.2 (21.48–1529.02) | 207.13 (21.48–1529.02) | 261.36 (99.81–525.00) | 0.95 |
Legend: PDR – proliferative diabetic retinopathy; NA- numerical areal density; CD45+ cells – leukocytes; CD3+ cells - T lymphocytes; CD4+ cells -(T helper lymphocytes; CD8+ cells - T cytotoxic lymphocytes; CD19+ cells - B lymphocytes; CD14+ cells - monocytes/macrophages