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. 2020 May 15;28(8):3593–3603. doi: 10.1007/s00520-020-05521-x

Table 2.

Patient details, lymphedema status, and exercise details of the independent studies published since September 2017 and details of previous studies published in Hasenoehrl et al. [11] and Keilani et al. [12]

Study Year Sample Patient details/LE status Exercise duration, frequency, intensity Exercise details Compression during RE
Ammitzbøll et al. [41] 2019

32

PRE: n = 16

Cont: n = 16

Patients undergoing BCa surgery with axillary lymph node dissection

Duration: 50 weeks: 20 weeks supervised + 30 weeks self-administered

Frequency: 3 times/week

RE intensity:

Progressing from 25 RM to 10–12 RM

Sets: 2–3

Rep/set:

Weeks 1–4: 15–20 repetitions at the 25 RM, 2–3 sets

Weeks 5–8: 15–17 repetitions at the 20 RM, 3 sets

Weeks 9–12: 10–12 repetitions at the 15 RM, 3 sets

Weeks 13–50: 10–12 repetitions at the 10–12 RM

Muscle groups: Major muscle groups for upper limb, lower limb, and core

Exercises used: Minimum of six exercises per session: three for the upper body, one for the lower body, and two for the core

Yes, if deemed necessary
Bloomquist et al. [42] 2018

18 in cross-over design

RE-HL: n = 18

RE-LL: n = 17

Women receiving standard adjuvant chemotherapy for stage I–III BCa

Duration: 2 single sessions over 2 weeks

Frequency:

1 RE session – 7 days washout – 1 RE session

RE intensity:

RE-HL: 85–90% 1RM

RE-LL: 60–65% 1RM

Rep/set:

RE-LL: 2 sets of 15–20 repetitions

RE-HL: 3 sets of 5–8 repetitions

Exercises/muscle groups:

Chest press, latissimus pulldown and triceps extension with exercise machines, biceps curls with free weights

No

Bloomquist et al. [43]

Additional information derived from Bloomquist et al. [43]

2019

153

High: n = 75

Low: n = 78

Physically inactive women receiving adjuvant chemotherapy for BCa

Duration: 12 weeks

Frequency: 3 times/week

RE intensity:

High: 85–90% 1RM

Low: no RE

Rep/set:

High:

Weeks 1–6: RE + AE + relaxation + massage

Week 1: 8–12 repetitions at 70% 1RM, 2–3 sets

Week 2: 8–12 repetitions at 80% 1RM, 2–3 sets

Weeks 3–12: 5–8 repetitions at 80–90% 1RM, 2–3 sets

Weeks 7–12: RE + AE + ballgames + dancing

Exercises/muscle group:

Major muscle groups of the body: leg press, chest press, latissimus pull down, abdominal crunch, lower back and knee extension

Low: walking + health consultation

No information
Luz et al. [45] 2018

42

CPT: n = 22

CPT + ST: n = 20

BCS diagnosed with LE resulting from unilateral surgery for BCa treatment

Duration: 8 weeks

Frequency: 2 times/week

RE intensity:

CPT: no RE

CPT + ST: 40% 1RM

Rep/set:

CPT: therapeutic exercises

CPT+ST:

Week 1: 10 repetitions, 2 sets

Week 2: 10 repetitions, 3 sets

Weeks 3–8: 15 repetitions, 3 sets

Exercises/muscle groups:

Shoulder abduction, elbow extension, external and internal rotation with resistance band, protraction/retraction of the shoulder blades with a stick, shoulder flexion and abduction, elbow flexion, fist flexion and extension with a sling, ball pressing and moving

Yes, part of the CPT
Omar et al. [44] 2019

70

RE + comp: n = 35

RE: n = 35

Women with unilateral BCRL and ≥ 5% of interlimb differences of volume or circumference

Duration: 8 weeks

Frequency: 3 times/week

RE intensity: 50–60% est1RM

Rep/set:

10–12 repetitions, 2–3 sets

Exercises/muscle groups:

Dumbbell fly, triceps extension, biceps curl up, one-arm bent over row, dumbbell sides rise, lifting the arm forward, and wrist curls with dumbbells

Yes, depending on personal preference

Schmitz et al. [46]

Additional information derived from Winkels et al. [51]

2019

351

Cont: n = 90

Exerc: n = 87

Weight loss: n = 87

Exerc + weight loss: n = 87

Overweight BCS with BCRL

Duration: 52 weeks

Frequency: 2 times/week

RE intensity: no information

Rep/set:

Exerc and exerc + weight loss

Weeks 1–6: 1 supervised session (exercise instruction) + 1 unsupervised

Weeks 1–4: 10 repetitions, 2 sets

Weeks 7–52: 2 home-based exercise sessions, 1 weekly support telephone call + 1 monthly in-person class

Weeks 5–52: 10 repetitions, 3 sets

Exercises/muscle groups:

Chest-presses, squats on a chair, one-arm rowing exercise, side-raises, step-ups, kickbacks, split-leg lunges, side lunges, and bicep curls with adjustable dumbbells + core training exercises of abdominal and lower back muscles (1 stabilization, 1 flexion, and 1 extension core exercise)

Yes

AE aerobic exercise, BCa breast cancer, BCRL breast cancer related lymphedema, BCS breast cancer survivor, Comp compression, Cont control group, CPT complex physical therapy, est1RM estimated 1-repetition-maximum, Exerc exercise, LE lymphedema, PRE progressive resistance exercise, Rep/set repetitions per set, RE resistance exercise, RE-LL low load resistance exercise, RE-HL high load resistance exercise, ST strength training, RM repetition-maximum