Table 1.
Admission demographic and clinical characteristics of the complete CHN cohort (n = 29) after dividing by hematoma location (lobar n = 16, and deep n = 13). Continuous variables are presented as median [interquartile range]. Intraventricular Hemorrhage (IVH), modified Rankin Scale (mRS), National Institute of Health Stroke Scale (NIHSS). Bold numbers indicate statistically significant p-values.
| ICH | Lobar ICH | Deep ICH | p value | |
|---|---|---|---|---|
| (n = 29) | (n = 16) | (n = 13) | ||
| Age (years) | 76 [66–85] | 72.5 [65–87] | 82.0 [68–85] | 0.442 |
| Sex (Female), n (%) | 11 (37.9) | 7 (43.8) | 4 (30.8) | 0.474 |
| Hypertension (Yes), n (%) | 15 (51.7) | 6 (37.5) | 9 (69.2) | 0.089 |
| Diabetes (Yes), n (%) | 7 (24.1) | 3 (18.8) | 4 (30.8) | 0.452 |
| Dyslipidemia (Yes), n (%) | 11 (37.9) | 7 (43.8) | 4 (30.8) | 0.474 |
| Glucose (mg/mL) | 133 [115-163] | 133 [110-163] | 128 [117-179] | 0.834 |
| Hematoma volume at admission (mL) | 18 [7–46] | 38 [19–69] | 8 [4–17] | <0.001 |
| Hematoma volume 24–48 h (mL) | 20 [5–46] | 42 [23–58] | 9.4 [3.6–18] | 0.004 |
| Hematoma growth (Yes), n (%) | 3 (11.5) | 1 (7.7) | 2 (15.4) | 0.539 |
| IVH (Yes), n (%) | 9 (31) | 7 (43.8) | 2 (15.4) | 0.101 |
| mRS at admission (Score) | 0 [0–0] | 0.0 [0–1] | 0.0 [0–0]) | 0.162 |
| mRS 90 days (Score) | 4 [2–6] | 4.0 [3–6] | 4.0 [2–6] | 0.534 |
| NIHSS at admission (Score) | 8 [4–17] | 9.0 [3–17.7] | 5.0 [4–16.5] | 0.965 |
| Mortality 90 days (Yes), n (%) | 9 (33.3) | 6 (42.9) | 3 (23.1) | 0.276 |
| MMP-1 (ng/mL) | 6.3 [3.5–12.1] | 4.8 [3.3–7.56] | 9.7 [4.1–13.7] | 0.200 |
| MMP-2 (ng/mL) | 110.5 [85.1–144.4] | 105.6 [82–134.6] | 111.6 [92.8–165] | 0.382 |
| MMP-7 (ng/mL) | 17.3 [14–22.5] | 15.3 [13–19] | 21.1 [15.5–24.3] | 0.048 |
| MMP-9 (ng/mL) | 237 [137.8–338] | 257.3 [115.7–334.4] | 223.8 [144–388] | 1 |
| MMP-10 (pg/mL) | 577.9 [439.3–855.4] | 485.1 [400–742.1] | 589.6 [473.6–936.4] | 0.216 |
| TIMP-1 (ng/mL) | 162.3 [139.8–225.1] | 166.5 [122.1–232.1] | 162.3 [146.5–222.4] | 0.913 |