Table 2.

Admission demographic and clinical characteristics of the complete VdH cohort (n = 76) after dividing by hematoma location (lobar n = 28, and deep n = 48). Continuous variables are presented as median [interquartile range]. Intraventricular Hemorrhage (IVH), modified Rankin Scale (mRS), National Institute of Health Stroke Scale (NIHSS). Bold numbers indicate statistically significant p-values.

	ICH	Lobar ICH	Deep ICH	p value
	(n = 76)	(n = 28)	(n = 48)
Age (years)	72 [66–80]	77 [68–82]	69 [65–77]	0.060
Sex (Female), n (%)	33 (43.4)	12(42.9)	21 (43.7)	1
Hypertension (Yes), n (%)	66 (86.8)	21 (75.0)	45 (93.7)	0.048
Diabetes (Yes), n (%)	21 (27.6)	10 (35.7)	11 (22.9)	0.348
Dyslipidemia (Yes), n (%)	46 (60.5)	19 (67.9)	27 (56.2)	0.450
Glucose (mg/mL)	128 [110–164]	141.5 [117–216.5]	124 [108–148]	0.037
Hematoma volume at admission (mL)	10.6 [3.9–35]	43.7 [15.5–77]	5.8 [3.2–19.3]	<0.0001
Hematoma volume 24–48 h (mL)	8 [3.6–37.1]	39 [20.2–48.1]	5.7 [3.3–14.8]	0.001
Hematoma growth (Yes), n (%)	12 (27.3)	3 (20.0)	9 (31.0)	0.673
IVH (Yes), n (%)	32 (42.1)	12 (42.9)	20 (41.7)	1
mRS at admission (Score)	0 [0–2]	0 [0–2]	0 [0–1.7]	0.782
mRS 90 days (Score)	4 [2–6]	5 [2–6]	3 [2–5.7]	0.198
NIHSS at admission (Score)	12 [6.7–19.2]	15 [9–21]	11 [6–19]	0.227
Mortality 90 days (Yes), n (%)	21 (31.3)	11 (45.8)	10 (23.3)	0.102
MMP-1 (ng/mL)	7.245 [3.9–11.9]	6.09 [2.9–11.5]	8.33 [5.4–12.3]	0.171
MMP-2 (ng/mL)	106.4 [83.7–116.6]	108.7 [83.7–115.3]	105.17 [83.7–117.0]	1
MMP-7 (ng/mL)	20.7 [16.0–27.6]	23.9 [16.3–31.8]	19.5 [16.0–26.4]	0.208
MMP-9 (ng/mL)	110.1 [78.3–160.4]	121.6 [78.3–205.1]	106.4 [77.6–140.4]	0.306
MMP-10 (pg/mL)	478.9 [297.7–710.4]	492.0 [290.4–963.0]	478.9 [297.7–599.2]	0.410
TIMP-1 (ng/mL)	202.9 [169.7–243.5]	225.4 [174.1–249.7]	199.2 [169.3–235.3]	0.294