Table 3.
Association of admission hematoma volume with clinical parameters and MMPs and TIMP-1 levels in the CHN cohort (n = 29). Intraventricular Hemorrhage (IVH), modified Rankin Scale (mRS), National Institute of Health Stroke Scale (NIHSS). Bold numbers indicate statistically significant p-values.
B (95% CI) | Beta | p value | |
---|---|---|---|
Age (years) | 0.52 (−0.87–1.90) | 0.15 | 0.450 |
Sex (Female) | −6.1 (−40.7–28.5) | −0.07 | 0.721 |
Hypertension | −32.2 (−63.4–0.94) | −0.38 | 0.044 |
Diabetes | −28.1 (−65.9–9.7) | −0.28 | 0.139 |
Dyslipidemia | −22.9 (−56.4–10.7) | −0.26 | 0.173 |
Glucose (mg/mL) | 0.22 (−0.17–0.60) | 0.22 | 0.262 |
Hematoma location (Lobar) | 43.7 (14.5–72.8) | 0.51 | 0.005 |
Hematoma growth | −9.1 (−32.4–14.2) | −0.16 | 0.426 |
IVH | 44.2 (12.2–76.2) | 0.48 | 0.008 |
mRS at admission (Score) | −11.9 (−40.6–16.6) | −0.16 | 0.398 |
mRS 90 days (Score) | 8.0 (−0.23–16.2) | 0.37 | 0.056 |
NIHSS at admission (Score) | 2.8 (1.14–4.41) | 0.56 | 0.002 |
Mortality 90 days | 46.0 (12.5–79.5) | 0.49 | 0.009 |
MMP-1 (ng/mL) | 0.31 (−1.06–1.70) | 0.10 | 0.639 |
MMP-2 (ng/mL) | 0.15 (−0.23–0.53) | 0.16 | 0.419 |
MMP-7 (ng/mL) | −1.69 (−3.80–0.42) | −0.32 | 0.112 |
MMP-9 (ng/mL) | −0.01 (−0.14–0.13) | −0.02 | 0.934 |
MMP-10 (pg/mL) | 0.02 (−0.03–0.07) | 0.14 | 0.480 |
TIMP-1 (ng/mL) | 0.19 (0.09–0.28) | 0.60 | 0.001 |