Table 4.
Association of admission hematoma volume with clinical parameters and MMPs and TIMP-1 levels in the VdH cohort (n = 76). Intraventricular Hemorrhage (IVH) modified Rankin Scale (mRS), National Institute of Health Stroke Scale (NIHSS). Bold numbers indicate statistically significant p-values.
| B (95% CI) | Beta | p value | |
|---|---|---|---|
| Age (years) | 1.33 (0.4–2.27) | 0.32 | 0.007 |
| Sex (Female) | −3.24 (−22.02–15.53) | −0.04 | 0.736 |
| Hypertension | −28.94 (−55.1–2.78) | −0.25 | 0.033 |
| Diabetes | 5.12 (−15.36–25.61) | 0.06 | 0.625 |
| Dyslipidemia | −14.28 (−32.97–4.41) | −0.18 | 0.139 |
| Glucose (mg/mL) | 0.25 (0.1–0.41) | 0.35 | 0.002 |
| Hematoma location (Lobar) | 46.22 (29.87–62.58) | 0.55 | <0.001 |
| Hematoma growth | −12.87 (−26.32–0.58) | −0.28 | 0.068 |
| IVH | 17.7 (−0.64–36.03) | 0.22 | 0.063 |
| mRS at admission (Score) | 6.11 (−0.9–13.12) | 0.20 | 0.092 |
| mRS 90 days (Score) | 10.9 (6.01–15.79) | 0.50 | <0.001 |
| NIHSS at admission (Score) | 2.05 (0.99–3.11) | 0.41 | <0.001 |
| Mortality 90 days | 48.72 (29.43–68.02) | 0.53 | <0.001 |
| MMP-1 (ng/mL) | 0.45 (−0.96–1.86) | 0.07 | 0.534 |
| MMP-2 (ng/mL) | 0.15 (−0.15–0.46) | 0.12 | 0.324 |
| MMP-7 (ng/mL) | 0.83 (0.32–1.34) | 0.36 | 0.002 |
| MMP-9 (ng/mL) | 0.05 (−0.04–0.14) | 0.12 | 0.308 |
| MMP-10 (pg/mL) | 0.01 (−0.01–0.03) | 0.14 | 0.236 |
| TIMP-1 (ng/mL) | 0.17 (0.03–0.32) | 0.27 | 0.022 |