Table 1.
Univariate and multivariate Cox proportional hazards model based on disease-free survival (DFS) in Image Set B testing set.
| Variable | Subtype | Univariate | Multivariate | ||||
|---|---|---|---|---|---|---|---|
| P | HR | 95%CI | P | HR | 95%CI | ||
| AI DFS status | High- vs. low-risk | 0.002 | 5.397 | 1.895–15.371 | 0.000 | 8.976 | 2.824–28.528 |
| Age(y) | >50 vs.≤50 | 0.241 | 2.418 | 0.553–10.579 | 0.081 | 4.417 | 0.832–23.437 |
| Gender | Male vs. Female | 0.982 | 1.011 | 0.391–2.611 | 0.395 | 0.580 | 0.165–2.037 |
| Tumor site | Left vs. Right colon | 0.132 | 0.482 | 0.186–1.247 | 0.115 | 0.420 | 0.143–1.235 |
| Tumor size | <5 cm vs. ≥5 cm | 0.924 | 1.046 | 0.412–2.655 | 0.276 | 0.496 | 0.141–1.752 |
| Histologic type | Muc + Sig vs. Ade | 0.119 | 2.692 | 0.774–9.336 | 0.817 | 1.260 | 0.178–8.921 |
| Histologic grade | G3 vs. G1 + G2 | 0.184 | 1.945 | 0.728–5.192 | 0.088 | 2.813 | 0.857–9.231 |
| pT | T4 vs. T1–3 | 0.056 | 2.540 | 0.977–6.602 | 0.036 | 3.080 | 1.079–8.792 |
| pN | N2 vs. N1 | 0.123 | 2.173 | 0.811–5.820 | 0.286 | 0.428 | 0.090–2.036 |
| TNM stage | III C vs. IIIA + IIIB | 0.025 | 2.909 | 1.145–7.392 | 0.005 | 4.354 | 1.573–12.051 |
Abbreviation: HR, hazard risk; CI, confidence interval; AI, artificial intelligence; Muc, mucous adenocarcinoma, Sig, signet ring cell adenocarcinoma; Ade, adenocarcinoma; G3, grade 3 (poor differentiation); G1, grade 1 (well differentiation); G2, grade 2 (moderated differentiation); pT, pathological primary tumor stage; pN, pathological lymph node stage; TNM, tumor, lymph node, and metastasis stage.