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BAM complex model and its mediated folding of OMPs in E. coli. The BAM complex consists of BamA, an OM β-barrel protein with five N-terminal POTRA domains, and the lipoproteins BamB–E. Nascent OMPs are translocated across the inner membrane (IM) into the periplasm. Chaperones such as SurA and Skp recognize unfolded OMPs in the periplasm and transport them to the BAM complex. The BAM complex receives, folds, and inserts OMPs at the OM.
