Table 3.
Objective knowledge using 10-item kids-KOGS.
| Study 1; N = 289 | Study 2; N = 265 | |||||
|---|---|---|---|---|---|---|
| Item | Pre | Post | Sig. | Pre | Post | Sig. |
| Genetics 101 | ||||||
| Item 1: Our DNA is inside our cells (true) | 248 (85.8%) | 260 (90.0%) | Z = −2.69, p = 0.007 | 213 (80.4%) | 238 (89.8%) | Z = −3.703, p = 0.000213 |
| Item 2: Our DNA doesn’t have an effect on how our body works (false) | 206 (71.3%) | 241 (83.4%) | Z = −4.52, p = 0.000006 | 178 (67.2%) | 207 (78.1%) | Z = −3.54, p = 0.000396 |
| Item 3: Our complete set of DNA is called our genome (true) | 53 (18.3%) | 254 (84.8%) | Z = −13.68, p = 1.38−42 | 70 (26.4%) | 207 (78.1%) | Z = −11.33, p = 9.97−30 |
| Item 4: Around 1% of our genome is the same as other people’s (false) | 39 (13.5%) | 212 (73.4%) | Z = −12.65, p = 1.10−36 | 38 (14.3%) | 167 (63.0%) | Z = −10.17, p = 2.79−24 |
| Item 5: Our genome is more similar to our close relatives, like our mum and dad, than it is with other people’s (true) | 150 (51.9%) | 247 (85.5%) | Z = −9.05, p = 1.50−19 | 173 (65.3%) | 237 (89.4%) | Z = −6.75, p = 1.52−11 |
| Item 7: A ‘glitch’ in the genome (like a spelling mistake) can cause a health problem because the body isn’t getting the right instructions (true) | 117 (40.5%) | 274 (94.8%) | Z = −12.53, p = 5.12−36 | 134 (50.6%) | 232 (87.5%) | Z = −9.34, p = 9.28−21 |
| Genome sequencing | ||||||
| Item 6: Genome sequencing involves looking at all the DNA in a person’s genome (true) | 66 (22.8%) | 189 (65.4%) | Z = −9.98, p = 1.94−23 | 59 (22.3%) | 170 (64.2%) | Z = −9.63, p = 6.28−22 |
| Item 8: Genome sequencing can be done on the DNA in a blood sample (true) | 71 (24.6%) | 265 (91.7%) | Z = −13.68, p = 1.31−42 | 74 (27.9%) | 232 (87.5%) | Z = −10.19, p = 2.22−24 |
| Limitations and uncertainties | ||||||
| Item 9: We know all there is to know about what our genome does (false) | 174 (60.2%) | 213 (73.7%) | Z = −4.67, p = 0.000003 | 153 (57.7%) | 182 (68.7%) | Z = −3.49, p = 0.000481 |
| Item 10: If someone with a health problem has genome sequencing, they will always find helpful information about the cause of the problem (false) | 71 (24.6%) | 98 (33.9%) | Z = −3.17, p = 0.002 | 61 (23.0%) | 143 (54.0%) | Z = −7.49, p = 6.97−14 |
Note: p values in bold indicate significance over 0.05