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. 2020 Jun 19;11:1346. doi: 10.3389/fmicb.2020.01346

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Copyright © 2020 Qiang, Wang, Xiong, Qu, Liu, Hu and Meng.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The β-carotene content and HMG-CoA content of the control strain Y.L-1, Y.L-3 overexpressing one copy of erg13, Y.L-4 overexpressing two copies of erg13, Y.L-5 overexpressing three copies of erg13, and Y.L-6 overexpressing Hxk and two copies of erg13 in YPD medium after 96 h of shake-flask fermentation. (A) The β-carotene content of Y.L-1, Y.L-3, Y.L-4, Y.L-5, and Y.L-6. (B) The HMG-CoA content of Y.L-1, Y.L-3, Y.L-4, Y.L-5, and Y.L-6. Error bars represent standard deviations (n = 3). The asterisks indicate a significant difference compared with the control (**p < 0.01).