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. 2020 Jun 19;11:610. doi: 10.3389/fgene.2020.00610

TABLE 3.

Semi-quantitative scoring system used for histopathological examination of gill tissue in sea farmed Atlantic salmon (adapted and modified from Mitchell et al., 2012).

Parameter Description
Index criteria with scores 0–31
LH Lamellar hyperplasia
LF Lamellar fusion
LO Lamellar oedema
CA Cellular anomalies
Ancillary criteria with scores 0–31
In Inflammation (presence of inflammatory cells outside blood vessels)
Eg Eosinophilic granular cells (numbers higher than normal in gill filaments)
Cc Chloride cells (numbers higher than normal and/or abnormal location)
Cd Circulatory disturbances (thrombi, telangiectasis, congestion)
Ib Interlamellar blood (hemorrhage)
Ch Cellular hypertrophy (hydropic degeneration of lamellar cells)
bE Epitheliocystis-like bacteria
bT Tenacibaculum-like bacteria (mats of filamentous bacteria on lamellar surfaces)
Ob Other bacteria
Pp Protist parasites, Neoparamoeba-like
Op Other parasites or agents

1Scoring system 0–3, with 0 = no pathological changes, 1 = mild changes affecting < 10% of gill tissue, 2 = moderate changes affecting 10–50% of gill tissue, and 3 = severe changes affecting > 50% of gill tissue.