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pA2 value estimates for compounds tested as B2 receptor antagonists using the umbilical vein contractility assay.
| Compound | Parameters calculated using Pharm/PCS (Figure 4) | |||
|---|---|---|---|---|
| pA2 | pA2 S.E.M. | Slope | Slope S.E.M. | |
| icatibant | 8.06 | 0.37 | −0.85 | 0.16 |
| Compound 1 | 8.58 | 0.26 | −0.62 | 0.07 |
| Compound 2 | 9.02 | 0.31 | −0.65 | 0.07 |
| Compound 3 | 9.67 | 0.42 | −0.76 | 0.13 |
