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. 2020 Jun 19;11:916. doi: 10.3389/fphar.2020.00916

Table 5.

Agonist EC50 values in specificity experiments (Figure 5).

Antagonist Agonist Antagonist concentration Agonist EC50 (nM) 95% confidence limits on EC50 values
Compound 2 Serotonin 0 7.5 5.9 – 9.5
10 μM 4.0 2.6 – 6.1
U-46619 0 24.9 17.2 – 36.2
10 μM 24.5 18.3 – 32.9
Compound 3 Serotonin 0 17.2 11.5 – 25.8
1 μM 20.5 14.5 – 28.9
U-46619 0 14.1 9.7 – 20.5
1 μM 11.3 8.8 – 15.5
Sar-[D-Phe8]des-Arg9-BK 0 92.0 62.9 – 134.7
1 μM 72.3 43.9 – 119.2
icatibant Sar-[D-Phe8]des-Arg9-BK 0 112.1 92.2 – 139.3
1 μM 68.2 42.5 – 109.4