Table 7.
Apparent BK EC50 values in the icatibant reversibility experiment (Figure 6D).
| Curve, time point | BK EC50 (nM) | 95% confidence limits on EC50 values |
|---|---|---|
| Vehicle, 3 h | 9.9 | 6.0 – 16.2 |
| Vehicle washout, 5 h | 19.5 | 11.8 – 32.5 |
| icatibant 1 μM, 3 h | 756 | 599 – 954 |
| icatibant washout, 5 h | 21.1 | 15.9 – 27.9 |