Table 1.
Groups | FBG (mmol/L) | INS (mIU/L) | HOMA-IR | ISI | GSP (mmol/L) | TNF-α (pg/mL) | IL-1β (pg/mL) | IL-6 (pg/mL) |
---|---|---|---|---|---|---|---|---|
Normal | 3.91 ± 0.29** | 15.76 ± 1.87** | 2.82 ± 0.51** | −4.05 ± 0.16** | 1.17 ± 0.09** | 125.31 ± 17.61** | 124.26 ± 22.09** | 120.66 ± 13.26** |
Model | 21.70 ± 0.56 | 27.08 ± 3.10 | 26.18 ± 3.24 | −6.33 ± 0.12 | 1.76 ± 0.06 | 299.03 ± 25.46 | 363.83 ± 42.05 | 257.66 ± 17.78 |
Metformin | 16.11 ± 0.68** | 18.76 ± 1.41* | 13.43 ± 1.15** | −5.69 ± 0.08** | 1.40 ± 0.05** | 156.04 ± 14.47** | 179.32 ± 31.43** | 151.94 ± 15.04** |
SY | 17.91 ± 0.44* | 18.81 ± 1.12* | 14.91 ± 0.84** | −5.81 ± 0.05* | 1.47 ± 0.06* | 189.42 ± 24.69** | 196.53 ± 28.80** | 166.06 ± 17.13** |
* and ** indicate P < 0.05 and P < 0.01, respectively.