Table 2.

Univariate and multivariate Cox regression analysis for overall survival according to combined NLR-PLR.

	Univariate		Multivariate	P-value
	HR (95%CI)	P-value	HR (95%CI)
Age (<60 vs ≥60)	0.984 (0.78–1.25)	0.892
Sex (female vs male)	1.00 (0.78–1.30)	0.973
History of gastric cancer operation (no vs. yes)	0.543 (0.43–0.69)	<0.001	0.589 (0.46–0.76)	<0.001
Intra-abdominal metastasis (no vs yes)	1.061 (0.84–1.35)	0.624
History of smoke (no vs. yes)	1.128 (0.88–1.44)	0.335
History of alcohol (no vs. yes)	1.037 (0.80–1.34)	0.779
Hypertension (no vs. yes)	1.116 (0.81–1.53)	0.496
Diabetes (no vs. yes)	1.352 (0.86–2.11)	0.185
CEA (<5 vs. ≥5)	1.248 (0.98–1.59)	0.071	1.163 (0.91–1.49)	0.231
CA199 (<37 vs. ≥37)	1.070 (0.84–1.37)	0.001	0.902 (0.70–1.16)	0.426
NLR-PLR	Ref	<0.001	Ref	<0.001
NLR-PLR(0/1)	1.525 (1.12–2.08)	0.007	1.487 (1.09–2.03)	0.012
NLR-PLR(0/2)	2.158 (1.62–2.87)	<0.001	1.886 (1.40–2.54)	<0.001
Differentiation (poor vs. moderate-well)	0.830 (0.66–1.05)	0.124	0.735 (0.58–0.94)	0.012