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Autophagy inhibition did not improve mitochondrial phenotype in 14-week-old mdx male mice. (A) Mitochondrial DNA copy number in quadriceps muscle (N = 5). (B) Protein expression in quadriceps muscle (N = 5). (C) HE, COX, and SDH staining in tibialis anterior muscle with the percentage of muscle fiber density shown right (N = 12). Scale bar = 0.1 mm. (D) Complex IV activity in quadriceps muscle (N = 5). Data presented as Mean ± SEM. *P < 0.05.
