Table 1.
MPNST cell lines in multiple research publications
| Name | Original reference(s) | Subject has NF1? (gender) | Tumor | Mutations: NF1 germline based on NM_0000267.3; TP53 specific somatic based on NM_000546.5. |
|---|---|---|---|---|
| ST-8814 | 78,79 | Yes (male) | n.a. | NF1 c.910 C>T exon skip |
| sNF96.2# | 26 | Yes (male) | Primary | NF1 c.3683delC |
| sNF02.2# | 80 | Yes (male) | Metastasis | NF1 c.4868A>T |
| sNF94.3# | 81 | Yes (female) | Metastasis | NF1 microdeletion |
| 88-3 | 82 | Yes (female) | Primary | NF1 c.6952T>C TP53 c.535C>T |
| 88-14 | 82 | Yes, recurrence of NF88-3 | Primary, recurrence | NF1 c.6952T>C TP53 c.535C>T |
| 90-8 (NF90-8) | 83,84 | Yes (female) | n.a. | NF1 microdeletion TP53 c.96 + 1G>A |
| T265 (T265-2c)* | 85 | Yes (n.a.) | n.a. | n.a. |
| S462 | 86 | Yes (female) | n.a. | TP53 c.389G>C |
| S520 | 86 | n.a. | n.a. | n.a. |
| STS26T | 87,88 | No (female) | Metastasis | TP53 homozygous deletion |
| S805 | 89 | Yes (n.a.) | n.a. | n.a. |
| MPNST-642 | 90 | Yes (male) | Primary, recurrence | n.a. |
| MPNST-724 | 57 | No | n.a. | TP53 c.280delTCA |
| Hs-Sch-2 | 91 | No (female) | Primary | TP53 c.818G>A |
| FU-SFT8611 | 92 | No (male) | Metastasis | n.a. |
| FU-SFT8710 | 92 | Yes (female) | Primary | n.a. |
| FU-SFT9817 | 92 | No (female) | Primary, recurrence | n.a. |
| NMS-2 | 93 | Yes (male) | Primary | n.a. |
| NMS-2PC | 93 | Yes, metastasis of NMS-2 | Metastasis | n.a. |
n.a., not available.
#Available in ATCC repository (atcc.org).
*Recent data suggest that T265 was overgrown by ST88-14 at a very early passage, so T265 data in the literature may not be reliable (Terribas, Gel, Serra, Wallace, Ratner, Largaespada, and others, in preparation).