Table 2.

Patients characteristics.

Patient	Age at diagnosis (y)	Neuro-developmental abnormalities	Localization	Histopathology
P1	2	CAL, Epilepsy, ADHD	Chiasma, Optical Nerves, Temporal Lobe, Optical Radiations	Pilocytic Astrocytoma
P2	6	Epilepsy, ADHD, Precocious Puberty, FH	Chiasma, Temporal Lobe, Intraventricular	Ganglioglioma
P3	0	Facial dysmorphia, Epilepsy, Macrocephaly, Stereotypies, Psychomotor Retardation, Growth Delay, FH	Chiasma, Thalamic and Peduncular lesions	Unclassifiable (PA vs GG)
P4	0	CAL, Facial dysmorphia, Macrocephaly, Stereotypies, Leukocoria	Chiasma, Optical Nerves, Peduncular lesions, Optical Radiations	Pilocytic Astrocytoma
P5	0	CAL, Intrauterine growth restriction, Psychomotor Retardation, Stereotypies, Growth Delay	Chiasma, Optical Nerves, Peduncular lesions, Optical Radiations	Pilocytic Astrocytoma
P6	4	Macrocephaly, Learning difficulties	Chiasma, Optical Nerves, Peduncular lesions, Optical Radiations	Pilocytic Astrocytoma
P7	5	Absence	Chiasma, Optical Nerves, Peduncular lesions, Optical Radiations	NSI
P8	2	Absence	Chiasma, Optical Nerves, Peduncular lesions, Optical Radiations	NSI
P9	2	Absence	Chiasma, Optical Nerves, Optical Tracts and Radiations	NSI
P10	10	CAL, Precocious Puberty	Chiasma, Optical tracts	NSI
P11	3	Absence	Chiasma, Thalamic and Peduncular lesions	Pilocytic Astrocytoma
P12	0	Absence	Chiasma, Peduncular lesions, Temporal Lobe, Optical Radiations	NSI
P13	2	Absence	Chiasma, Optical Nerves, Thalamic and Peduncular lesions	Pilocytic Astrocytoma
P14	2	Absence	Chiasma, Optical Radiations	Pilocytic Astrocytoma
P15	1	CAL, FH	Chiasma, Optical Radiations	Pilocytic Astrocytoma
P16	1	Growth Delay	Chiasma, Optical Radiations	Pilocytic Astrocytoma

ADHD, attention-deficit/hyperactivity disorder; CAL, café-au-lait spots; FH, family history of low-grade glioma/neurodevelopmental syndrome; GG: Ganglioglioma; NSI, no surgical intervention; PA: Pilocytic Astrocytoma.